$ t_ {1 \ rho} $映射是一种有希望的定量MRI技术，用于对组织性质的非侵入性评估。基于学习的方法可以从减少数量的$ t_ {1 \ rho} $加权图像中映射$ t_ {1 \ rho} $，但需要大量的高质量培训数据。此外，现有方法不提供$ t_ {1 \ rho} $估计的置信度。为了解决这些问题，我们提出了一个自我监督的学习神经网络，该网络使用学习过程中的放松约束来学习$ t_ {1 \ rho} $映射。为$ t_ {1 \ rho} $量化网络建立了认知不确定性和态度不确定性，以提供$ t_ {1 \ rho} $映射的贝叶斯置信度估计。不确定性估计还可以使模型规范化，以防止其学习不完美的数据。我们对52例非酒精性脂肪肝病患者收集的$ T_ {1 \ rho} $数据进行了实验。结果表明，我们的方法优于$ t_ {1 \ rho} $量化肝脏的现有方法，使用少于两个$ t_ {1 \ rho} $加权图像。我们的不确定性估计提供了一种可行的方法，可以建模基于自我监督学习的$ t_ {1 \ rho} $估计的信心，这与肝脏中的现实$ t_ {1 \ rho} $成像是一致的。

A further understanding of cause and effect within observational data is critical across many domains, such as economics, health care, public policy, web mining, online advertising, and marketing campaigns. Although significant advances have been made to overcome the challenges in causal effect estimation with observational data, such as missing counterfactual outcomes and selection bias between treatment and control groups, the existing methods mainly focus on source-specific and stationary observational data. Such learning strategies assume that all observational data are already available during the training phase and from only one source. This practical concern of accessibility is ubiquitous in various academic and industrial applications. That's what it boiled down to: in the era of big data, we face new challenges in causal inference with observational data, i.e., the extensibility for incrementally available observational data, the adaptability for extra domain adaptation problem except for the imbalance between treatment and control groups, and the accessibility for an enormous amount of data. In this position paper, we formally define the problem of continual treatment effect estimation, describe its research challenges, and then present possible solutions to this problem. Moreover, we will discuss future research directions on this topic.

Methods based on ordinary differential equations (ODEs) are widely used to build generative models of time-series. In addition to high computational overhead due to explicitly computing hidden states recurrence, existing ODE-based models fall short in learning sequence data with sharp transitions - common in many real-world systems - due to numerical challenges during optimization. In this work, we propose LS4, a generative model for sequences with latent variables evolving according to a state space ODE to increase modeling capacity. Inspired by recent deep state space models (S4), we achieve speedups by leveraging a convolutional representation of LS4 which bypasses the explicit evaluation of hidden states. We show that LS4 significantly outperforms previous continuous-time generative models in terms of marginal distribution, classification, and prediction scores on real-world datasets in the Monash Forecasting Repository, and is capable of modeling highly stochastic data with sharp temporal transitions. LS4 sets state-of-the-art for continuous-time latent generative models, with significant improvement of mean squared error and tighter variational lower bounds on irregularly-sampled datasets, while also being x100 faster than other baselines on long sequences.

Text-based speech editing allows users to edit speech by intuitively cutting, copying, and pasting text to speed up the process of editing speech. In the previous work, CampNet (context-aware mask prediction network) is proposed to realize text-based speech editing, significantly improving the quality of edited speech. This paper aims at a new task: adding emotional effect to the editing speech during the text-based speech editing to make the generated speech more expressive. To achieve this task, we propose Emo-CampNet (emotion CampNet), which can provide the option of emotional attributes for the generated speech in text-based speech editing and has the one-shot ability to edit unseen speakers' speech. Firstly, we propose an end-to-end emotion-selectable text-based speech editing model. The key idea of the model is to control the emotion of generated speech by introducing additional emotion attributes based on the context-aware mask prediction network. Secondly, to prevent the emotion of the generated speech from being interfered by the emotional components in the original speech, a neutral content generator is proposed to remove the emotion from the original speech, which is optimized by the generative adversarial framework. Thirdly, two data augmentation methods are proposed to enrich the emotional and pronunciation information in the training set, which can enable the model to edit the unseen speaker's speech. The experimental results that 1) Emo-CampNet can effectively control the emotion of the generated speech in the process of text-based speech editing; And can edit unseen speakers' speech. 2) Detailed ablation experiments further prove the effectiveness of emotional selectivity and data augmentation methods. The demo page is available at https://hairuo55.github.io/Emo-CampNet/

In this work, we study the black-box targeted attack problem from the model discrepancy perspective. On the theoretical side, we present a generalization error bound for black-box targeted attacks, which gives a rigorous theoretical analysis for guaranteeing the success of the attack. We reveal that the attack error on a target model mainly depends on empirical attack error on the substitute model and the maximum model discrepancy among substitute models. On the algorithmic side, we derive a new algorithm for black-box targeted attacks based on our theoretical analysis, in which we additionally minimize the maximum model discrepancy(M3D) of the substitute models when training the generator to generate adversarial examples. In this way, our model is capable of crafting highly transferable adversarial examples that are robust to the model variation, thus improving the success rate for attacking the black-box model. We conduct extensive experiments on the ImageNet dataset with different classification models, and our proposed approach outperforms existing state-of-the-art methods by a significant margin. Our codes will be released.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Event-based simulations of Spiking Neural Networks (SNNs) are fast and accurate. However, they are rarely used in the context of event-based gradient descent because their implementations on GPUs are difficult. Discretization with the forward Euler method is instead often used with gradient descent techniques but has the disadvantage of being computationally expensive. Moreover, the lack of precision of discretized simulations can create mismatches between the simulated models and analog neuromorphic hardware. In this work, we propose a new exact error-backpropagation through spikes method for SNNs, extending Fast \& Deep to multiple spikes per neuron. We show that our method can be efficiently implemented on GPUs in a fully event-based manner, making it fast to compute and precise enough for analog neuromorphic hardware. Compared to the original Fast \& Deep and the current state-of-the-art event-based gradient-descent algorithms, we demonstrate increased performance on several benchmark datasets with both feedforward and convolutional SNNs. In particular, we show that multi-spike SNNs can have advantages over single-spike networks in terms of convergence, sparsity, classification latency and sensitivity to the dead neuron problem.

The error Backpropagation algorithm (BP) is a key method for training deep neural networks. While performant, it is also resource-demanding in terms of computation, memory usage and energy. This makes it unsuitable for online learning on edge devices that require a high processing rate and low energy consumption. More importantly, BP does not take advantage of the parallelism and local characteristics offered by dedicated neural processors. There is therefore a demand for alternative algorithms to BP that could improve the latency, memory requirements, and energy footprint of neural networks on hardware. In this work, we propose a novel method based on Direct Feedback Alignment (DFA) which uses Forward-Mode Automatic Differentiation to estimate backpropagation paths and learn feedback connections in an online manner. We experimentally show that Directional DFA achieves performances that are closer to BP than other feedback methods on several benchmark datasets and architectures while benefiting from the locality and parallelization characteristics of DFA. Moreover, we show that, unlike other feedback learning algorithms, our method provides stable learning for convolution layers.

Copy-Paste is a simple and effective data augmentation strategy for instance segmentation. By randomly pasting object instances onto new background images, it creates new training data for free and significantly boosts the segmentation performance, especially for rare object categories. Although diverse, high-quality object instances used in Copy-Paste result in more performance gain, previous works utilize object instances either from human-annotated instance segmentation datasets or rendered from 3D object models, and both approaches are too expensive to scale up to obtain good diversity. In this paper, we revisit Copy-Paste at scale with the power of newly emerged zero-shot recognition models (e.g., CLIP) and text2image models (e.g., StableDiffusion). We demonstrate for the first time that using a text2image model to generate images or zero-shot recognition model to filter noisily crawled images for different object categories is a feasible way to make Copy-Paste truly scalable. To make such success happen, we design a data acquisition and processing framework, dubbed "X-Paste", upon which a systematic study is conducted. On the LVIS dataset, X-Paste provides impressive improvements over the strong baseline CenterNet2 with Swin-L as the backbone. Specifically, it archives +2.6 box AP and +2.1 mask AP gains on all classes and even more significant gains with +6.8 box AP +6.5 mask AP on long-tail classes.

Traditional learning-based approaches to student modeling (e.g., predicting grades based on measured activities) generalize poorly to underrepresented/minority student groups due to biases in data availability. In this paper, we propose a Multi-Layer Personalized Federated Learning (MLPFL) methodology which optimizes inference accuracy over different layers of student grouping criteria, such as by course and by demographic subgroups within each course. In our approach, personalized models for individual student subgroups are derived from a global model, which is trained in a distributed fashion via meta-gradient updates that account for subgroup heterogeneity while preserving modeling commonalities that exist across the full dataset. To evaluate our methodology, we consider case studies of two popular downstream student modeling tasks, knowledge tracing and outcome prediction, which leverage multiple modalities of student behavior (e.g., visits to lecture videos and participation on forums) in model training. Experiments on three real-world datasets from online courses demonstrate that our approach obtains substantial improvements over existing student modeling baselines in terms of increasing the average and decreasing the variance of prediction quality across different student subgroups. Visual analysis of the resulting students' knowledge state embeddings confirm that our personalization methodology extracts activity patterns which cluster into different student subgroups, consistent with the performance enhancements we obtain over the baselines.